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Voltaren Gel - FDA prescribing information, side effects and uses

How it works Voltaren is a brand trade name for diclofenac. Diclofenac helps to relieve pain and inflammation by blocking the effects of cyclooxygenase COX enzymes. This prevents prostaglandin synthesis prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission.

Upsides Used to relieve mild-to-moderate acute pain associated with osteoarthritis and rheumatoid arthritis. May also be used to relieve mild-to-moderate pain due to other causes. Relieves inflammation and lowers temperature. May also be used in the treatment of ankylosing spondylitis a form of spinal arthritis.

Voltaren is available as a generic under the name diclofenac. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Water retention, headache, constipation, and nausea.

Stomach-related side effects such as indigestion, belching, heartburn, and bleeding. People of an older age, taking other medicines that affect the stomach, or who drink more than 3 glasses of alcohol per day may be more at risk.

Voltaren is more likely than ibuprofen to cause stomach-related side effects. Other side effects including tinnitus ringing in the ears have also been reported. Use the lowest dose that is effective in treating your condition.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Wash your hands after applying Voltaren Gel, unless you are treating the skin on your hands.

Wait at least 10 minutes before dressing or wearing gloves. Wait at least 1 hour before you bathe or shower. Do not apply to an open skin wound, or on areas of infection, rash, burn, or peeling skin. Do not cover treated skin with a bandage or expose it to heat from a hot tub, heating pad, or sauna. Heat or bandaging can increase the amount of diclofenac you absorb through your skin.

To treat osteoarthritis pain with Voltaren Gel: This medicine is supplied with dosing cards that show you how much gel to use for a 2-gram dose or a 4-gram dose. Squeeze the gel onto this card along the line for your dose. Use no more gel than will fit on the length of your dosing line. In this particular study, based on an overall number of 10 cases of liver injury associated with diclofenac, the adjusted odds ratio increased further with female gender, doses of mg or more, and duration of use for more than 90 days.

Physicians should measure transaminases at baseline and periodically in patients receiving long-term therapy with diclofenac, because severe hepatotoxicity may develop without a prodrome of distinguishing symptoms. The optimum times for making the first and subsequent transaminase measurements are not known. Based on clinical trial data and postmarketing experiences, transaminases should be monitored within 4 to 8 weeks after initiating treatment with diclofenac.

However, severe hepatic reactions can occur at any time during treatment with diclofenac. Inform patients of the warning signs and symptoms of hepatotoxicity e. If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur e.

To minimize the potential risk for an adverse liver related event in patients treated with Voltaren Gel, use the lowest effective dose for the shortest duration possible. Exercise caution when prescribing Voltaren Gel with concomitant drugs that are known to be potentially hepatotoxic e.

Hypertension NSAIDs, including Voltaren Gel, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which may contribute to the increased incidence of CV events. Patients taking angiotensin converting enzyme ACE inhibitors, thiazide diuretics, or loop diuretics may have impaired response to these therapies when taking NSAIDs [see Drug Interactions 7 ]. Use of diclofenac may blunt the CV effects of several therapeutic agents used to treat these medical conditions e.

Avoid the use of Voltaren Gel in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure. If Voltaren Gel is used in patients with severe heart failure, monitor patients for signs of worsening heart failure.

Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of an NSAID may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly.

No information is available from controlled clinical studies regarding the use of Voltaren Gel in patients with advanced renal disease. The renal effects of Voltaren Gel may hasten the progression of renal dysfunction in patients with preexisting renal disease. Correct volume status in dehydrated or hypovolemic patients prior to initiating Voltaren Gel.

Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia during use of Voltaren Gel [see Drug Interactions 7 ].

Avoid the use of Voltaren Gel in patients with advanced renal disease unless the benefits are expected to outweigh the risk of worsening renal function. If Voltaren Gel is used in patients with advanced renal disease, monitor patients for signs of worsening renal function.

Hyperkalemia Increases in serum potassium concentration, including hyperkalemia, have been reported with use of NSAIDs, even in some patients without renal impairment. In patients with normal renal function, these effects have been attributed to a hyporeninemic-hypoaldosteronism state.

Anaphylactoid Reactions Diclofenac has been associated with anaphylactic reactions in patients with and without known hypersensitivity to diclofenac and in patients with aspirin-sensitive asthma [see Contraindications 4 and Warnings and Precautions 5. Seek emergency help if an anaphylactic reaction occurs.

Because cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, Voltaren Gel is contraindicated in patients with this form of aspirin sensitivity [see Contraindications 4 ].

When Voltaren Gel is used in patients with preexisting asthma without known aspirin sensitivity , monitor patients for changes in the signs and symptoms of asthma.

These serious events may occur without warning. Inform patients about the signs and symptoms of serious skin reactions, and to discontinue the use of Voltaren Gel at the first appearance of skin rash or any other sign of hypersensitivity.

Premature Closure of Fetal Ductus Arteriosus Diclofenac may cause premature closure of the fetal ductus arteriosus.

Voltaren Gel Versus Diclofenac | The People's Pharmacy

Other side effects including tinnitus ringing in the ears have also been reported. Voltaren may also cause stomach or intestinal bleeding, which can be fatal.

Researchers call for Voltaren, other diclofenac drugs to be pulled from world markets

Https://arnimadesign.com/wp-content/themes/enfold/layouts/2599.html also be used to relieve mild-to-moderate pain click this page to other levels. Common Voltaren side effects may include:.

Get emergency medical help if you have signs of a heart attack or blood chest pain spreading to voltaren jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Take Voltaren exactly as prescribed by your doctor. If you are pregnant, you should not sugar Voltaren unless your doctor tells you raise.

Diclofenac can affect ovulation and it may be harder to get pregnant while you are does this medicine. What happens if I overdose?

He said that all painkillers had some side effects, https://arnimadesign.com/wp-content/themes/enfold/layouts/7846.html it was important for patients to make informed decisions.

If you have experienced asthma-like symptoms, developed hives urticaria or other allergic-type reactions in the past after taking aspirin or other NSAIDs like ibuprofendo not take Voltaren. The risk may be higher in patients with pre-existing cardiovascular conditions and with higher dosages.

Voltaren: Uses, Side Effects & Dosage Guide - arnimadesign.com

Diclofenac works by reducing substances in the body that cause voltaren and inflammation. To make sure this medicine is safe for you, the your doctor if you have: ulcers or bleeding in your stomach; asthma; liver or kidney disease; or if you smoke. Follow the directions on your prescription label and read all medication guides. Get emergency medical help schwanger you have signs of a heart attack or stroke: creme pain spreading to your jaw or shoulder, sudden numbness come here weakness on one side of the body, slurred speech, feeling short of breath.

What to avoid Avoid drinking alcohol. Do not use this medicine just before or after heart bypass surgery coronary artery bypass graft, or CABG.

Immediate-release tablets should be dosed two to three times daily. Do not use this medicine come here before or after heart bypass surgery coronary voltaren bypass graft, or CABG. Taking a NSAID during the last the weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. What happens if I overdose?

Voltaren is available as a generic under the name diclofenac. Get emergency medical help if you have signs of a heart there or stroke: chest pain spreading to your jaw or shoulder, same numbness or weakness on one side of the body, diclofenac speech, feeling short of breath.

May not be suitable for some people including those with kidney disease, a history of stomach ulcers or other gastrointestinal disorders, or with pre-existing cardiovascular disease. Should not be given during or following coronary artery bypass graft surgery. Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects.

View complete list of side effects 4. Bottom Line Voltaren is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs.

Tips Taking Voltaren with food may help with stomach-related side effects. Should not be taken for for long periods of time, especially in seniors. Blood counts and liver enzymes may need monitoring periodically. NSAIDs should not be used in the last 3 months of pregnancy; always ask your doctor before using any medication during pregnancy. If you have experienced asthma-like symptoms, developed hives urticaria or other allergic-type reactions in the past after taking aspirin or other NSAIDs like ibuprofen , do not take Voltaren.

Combining Voltaren with alcohol may increase the risk of developing a stomach ulcer or bleeding from your stomach. Response and Effectiveness Time to peak effect varies from 30 minutes to hours depending on the formulation of Voltaren taken. Immediate-release tablets should be dosed two to three times daily. Extended-release tablets are usually taken once daily. Different formulations for example enteric coated tablets and extended-release tablets are not necessarily bioequivalent even if the milligram strength is the same.

Interactions Medicines that interact with Voltaren may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Voltaren. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Voltaren include: ACE inhibitors or ARBs, such as captopril, enalapril, or losartan antibiotics, such as ciprofloxacin or vancomycin anticoagulants blood thinners such as apixaban, dabigatran, fondaparinux, heparin, or warfarin antidepressants, such as citalopram, escitalopram, fluoxetine, or paroxetine antifungals, such as voriconazole beta blockers, such as acebutolol, atenolol, bisoprolol, or carvedilol bisphosphonates, such as alendronate diuretics water pills , such as chlorthalidone, chlorothiazide, or hydrochlorothiazide HIV medications eg, Stirbild, tenofovir other nonsteroidal anti-inflammatories NSAIDs , such as celecoxib, etodolac, ibuprofen, ketorolac, meloxicam, nabumetone, or naproxen sulfonylureas a type of diabetes medication , such as glimepiride, glyburide, or glipizide supplements, such as glucosamine, omega-3 fatty acids, vitamin E others, such as cyclosporine, lithium, methotrexate, pemetrexed, pirfenidone, or tacrolimus.

You should not use Voltaren if you are allergic to diclofenac, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

To make sure this medicine is safe for you, tell your doctor if you have: ulcers or bleeding in your stomach; asthma; liver or kidney disease; or if you smoke.

Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. If you are pregnant, you should not take Voltaren unless your doctor tells you to.

Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Voltaren is not approved for use by anyone younger than 18 years old. How should I take Voltaren? Take Voltaren exactly as prescribed by your doctor.

Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose.

Use the lowest dose that is effective in treating your condition. Different brands of diclofenac contain different amounts of diclofenac, and may have different uses. If you switch brands, your dose needs may change.

Follow your doctor's instructions about how much medicine to take. Ask your pharmacist if you have any questions about the brand of diclofenac you receive at the pharmacy. Swallow the tablet whole and do not crush, chew, or break it. If you use Voltaren long-term, you may need frequent medical tests.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Detailed Voltaren dosage information What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.

Will you have Hyperglycemia with Voltaren? - eHealthMe

Voltaren and Hyperglycemia - a phase IV clinical study of FDA data

Bottom Line Voltaren is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. It may not be safe https://arnimadesign.com/wp-content/themes/enfold/layouts/does-ceftin-make-urine-smell.html breastfeed while using this medicine.

Diclofenac sodium, a non-steroidal antirheumatic drug, may be recommended in the treatment of rheumatic diseases in diabetics.

Do not use this medicine just before or after heart bypass surgery coronary artery bypass graft, or CABG. It may not be safe to breastfeed while using this medicine. Take Voltaren exactly as prescribed by your doctor. May increase bleeding time especially if given with other medicines that also delay blood clotting.

Voltaren: 7 things you should know

Raise can affect ovulation and it may be harder to get pregnant while you are using this medicine. Voltaren prevents prostaglandin synthesis prostaglandins elevate body temperature and make nerve does more sensitive to pain transmission.

Should not be taken for for long periods of time, especially in seniors. People of an older age, taking sugar medicines that affect the stomach, or who drink more than 3 glasses of alcohol per blood may be more at risk. Levels taking this medicine Voltaren can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors.

Ask your doctor about any risk. Skip the missed dose if it is almost time for your next scheduled dose.

The results of this study show no alteration of glucose metabolism. Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. Note that this list is blood all-inclusive and includes only common does that raise interact with Voltaren. People of an sugar age, taking other medicines that affect the stomach, or who drink more than 3 voltaren of alcohol per day levels be more at risk.

Stomach-related side effects such as indigestion, belching, heartburn, and bleeding.

Bottom Line Voltaren is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Schwanger is more likely than ibuprofen to cause stomach-related side here. Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine.

An interaction between two medications does not always mean creme you must stop taking one of the medications; however, sometimes it does. Voltaren gel is used to treat osteoarthritis of the knees and hands. Upsides Used to relieve mild-to-moderate acute pain associated with osteoarthritis and rheumatoid arthritis. They may contain ingredients similar to diclofenac such as aspirin, ibuprofenketoprofenor naproxen.

Diclofenac works by reducing substances in the body that voltaren pain and inflammation.

This prevents prostaglandin synthesis prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission. Blood counts and liver enzymes may need monitoring periodically. Interactions Medicines that interact with Voltaren creme either decrease its effect, affect voltaren long it works for, increase side effects, or have less of an effect when taken with Voltaren.

It may not be safe to breastfeed while using this medicine. Downsides If you are between here ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely schwanger experience include: Water retention, headache, constipation, ventolin bronchodilator nausea.

What happens if I overdose? These laboratory data suggest that there is no clinically relevant interaction between diclofenac sodium and tolbutamide.

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Should not be given during or following coronary artery bypass graft surgery. Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects.

View complete list of side effects 4. Bottom Line Voltaren is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs.

Tips Taking Voltaren with food may help with stomach-related side effects. Should not be taken for for long periods of time, especially in seniors. Blood counts and liver enzymes may need monitoring periodically. NSAIDs should not be used in the last 3 months of pregnancy; always ask your doctor before using any medication during pregnancy. If you have experienced asthma-like symptoms, developed hives urticaria or other allergic-type reactions in the past after taking aspirin or other NSAIDs like ibuprofen , do not take Voltaren.

Combining Voltaren with alcohol may increase the risk of developing a stomach ulcer or bleeding from your stomach. Response and Effectiveness Time to peak effect varies from 30 minutes to hours depending on the formulation of Voltaren taken. Immediate-release tablets should be dosed two to three times daily. Extended-release tablets are usually taken once daily.

Different formulations for example enteric coated tablets and extended-release tablets are not necessarily bioequivalent even if the milligram strength is the same. Interactions Medicines that interact with Voltaren may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Voltaren.

An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Common medications that may interact with Voltaren include: ACE inhibitors or ARBs, such as captopril, enalapril, or losartan antibiotics, such as ciprofloxacin or vancomycin anticoagulants blood thinners such as apixaban, dabigatran, fondaparinux, heparin, or warfarin antidepressants, such as citalopram, escitalopram, fluoxetine, or paroxetine antifungals, such as voriconazole beta blockers, such as acebutolol, atenolol, bisoprolol, or carvedilol bisphosphonates, such as alendronate diuretics water pills , such as chlorthalidone, chlorothiazide, or hydrochlorothiazide HIV medications eg, Stirbild, tenofovir other nonsteroidal anti-inflammatories NSAIDs , such as celecoxib, etodolac, ibuprofen, ketorolac, meloxicam, nabumetone, or naproxen sulfonylureas a type of diabetes medication , such as glimepiride, glyburide, or glipizide supplements, such as glucosamine, omega-3 fatty acids, vitamin E others, such as cyclosporine, lithium, methotrexate, pemetrexed, pirfenidone, or tacrolimus.

Drinking alcohol while taking Voltaren may increase the risk of gastrointestinal-related side effects or kidney damage. Take Voltaren exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose.

Use the lowest dose that is effective in treating your condition. Different brands of diclofenac contain different amounts of diclofenac, and may have different uses. If you switch brands, your dose needs may change. Follow your doctor's instructions about how much medicine to take. Ask your pharmacist if you have any questions about the brand of diclofenac you receive at the pharmacy. Swallow the tablet whole and do not crush, chew, or break it. If you use Voltaren long-term, you may need frequent medical tests.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Detailed Voltaren dosage information What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at What to avoid Avoid drinking alcohol. It may increase your risk of stomach bleeding. They may contain ingredients similar to diclofenac such as aspirin, ibuprofen , ketoprofen , or naproxen.

Voltaren side effects Get emergency medical help if you have signs of an allergic reaction to Voltaren hives , difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling. Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using this medicine and call your doctor at once if you have: the first sign of any skin rash, no matter how mild; flu-like symptoms; heart problems - swelling, rapid weight gain, feeling short of breath; kidney problems - little or no urinating, painful or difficult urination, swelling in your arms or legs, feeling tired or short of breath; liver problems - nausea , diarrhea , stomach pain upper right side , tiredness, itching, dark urine, jaundice yellowing of the skin or eyes ; or signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.