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any one have lower back pain from Bactrim?

His doctors said it was an allergic reaction to the medication and put him on prednisone.

I've been taking bactrim for 7 days for a vaginal infection. Urgent Care,due to the fact my private Drs. The side affects can be deadly.

When you have these symptoms, you may assume you have a problem with your spine. Advertising Policy Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. For example, lumbar spinal stenosis is a nerve problem and peripheral arterial disease is related to blood flow, but the two have many symptoms in common. So do spinal stenosis and diabetic neuropathy, or nerve damage in the legs and feet.

And disk issues can feel a lot like inflammatory arthritis. When back pain is likely spinal stenosis Spinal stenosis is one of the most common causes of spinal pain not related to injury. This narrowing of the space around the spinal cord puts pressure on the nerves. If you have the following symptoms, spinal stenosis may be to blame: Pain in the lower back. Cramping in the legs. A heavy feeling in the legs, which may lead to trouble walking. Increased pain going downhill.

Symptoms that get worse with activity. However, Dr. Check out our list of 22 high-fiber foods. Begin a regular bowel movement schedule. Over-the-counter stool softeners, suppositories, and laxatives can help with temporary constipation.

You can also try natural stool softeners and laxatives. For cases of chronic constipation, your doctor can help treat the underlying cause.

Talk to your doctor about evaluating your back pain. Outlook With a change of diet and increased water consumption, constipation often resolves on its own.

Sometimes when constipation is resolved, back pain lessens or disappears. If not, talk to your doctor specifically about treatment to relieve your back pain.

If your constipation and back pain are severe, see your doctor as soon as possible.

Bactrim - FDA prescribing information, side effects and uses

Causing all directions on your prescription label and read all medication guides or instruction sheets. Urinary Tract Back For the treatment of urinary tract infections due to susceptible strains of the causing organisms: Escherichia coli, Klebsiella species, Enterobacter species, Morganella morganii, Proteus mirabilis and Proteus vulgaris.

Further information Always consult your healthcare provider to ensure the information pain on this page applies to your personal bactrim. Electrolyte Abnormalities Bactrim dosage of trimethoprim, pain used in back with P.

Bactrim may inhibit the hepatic metabolism hypoglycemia phenytoin a CYP2C9 substrate. Appropriate fluid and electrolyte management, protein supplementation, here treatment of C. Trimethoprim alone was negative in in vitro reverse mutation bacterial assays and in in vitro chromosomal aberration assays bactrim Chinese Hamster ovary or lung cells with or without S9 activation.

Evaluation for hyponatremia and appropriate correction is necessary in symptomatic patients to prevent life-threatening complications. This includes prescription and over-the-counter medicines, vitaminsand herbal products.

Exclusivity periods can run from days to seven years depending upon the circumstance of the exclusivity grant. By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. AB Products meeting necessary bioequivalence requirements.

Multisource drug products listed under the same heading i. Pneumocystis jirovecii Pneumonia: For the treatment of documented Pneumocystis jirovecii pneumonia and for prophylaxis against P. Traveler's Diarrhea in Adults: For the treatment of traveler's diarrhea due to susceptible strains of enterotoxigenic E. Bactrim is contraindicated in pediatric patients less than 2 months of age.

Bactrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored. Hypersensitivity and Other Fatal Reactions Fatalities associated with the administration of sulfonamides, although rare, have occurred due to severe reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia and other blood dyscrasias. Clinical signs, such as rash, sore throat, fever, arthralgia, pallor, purpura or jaundice may be early indications of serious reactions.

Cough, shortness of breath, and pulmonary infiltrates are hypersensitivity reactions of the respiratory tract that have been reported in association with sulfonamide treatment. Severe cases of thrombocytopenia that are fatal or life threatening have been reported.

In an established infection, they will not eradicate the streptococcus and, therefore, will not prevent sequelae such as rheumatic fever. Clostridioides difficile associated diarrhea Clostridioides difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Bactrim, and may range in severity from mild diarrhea to fatal colitis.

Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibiotic use.

Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Adjunctive treatment with Leucovorin for Pneumocystis jirovecii pneumonia Treatment failure and excess mortality were observed when trimethoprim-sulfamethoxazole was used concomitantly with leucovorin for the treatment of HIV positive patients with Pneumocystis jirovecii pneumonia in a randomized placebo controlled trial.

Precautions Development of drug resistant bacteria Prescribing Bactrim sulfamethoxazole and trimethoprim tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Folate deficiency Bactrim should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency e. Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure.

These effects are reversible by folinic acid therapy. Hemolysis In glucosephosphate dehydrogenase deficient individuals, hemolysis may occur. Hypoglycemia Cases of hypoglycemia in non-diabetic patients treated with Bactrim are seen rarely, usually occurring after a few days of therapy.

Patients with renal dysfunction, liver disease, malnutrition or those receiving high doses of Bactrim are particularly at risk. Phenylalanine metabolism Trimethoprim has been noted to impair phenylalanine metabolism, but this is of no significance in phenylketonuric patients on appropriate dietary restriction.

Porphyria and Hypothyroidism As with all drugs containing sulfonamides, caution is advisable in patients with porphyria or thyroid dysfunction. The incidence of side effects, particularly rash, fever, leukopenia and elevated aminotransferase transaminase values, with Bactrim therapy in AIDS patients who are being treated for P.

Adverse effects are generally less severe in patients receiving Bactrim for prophylaxis. A history of mild intolerance to Bactrim in AIDS patients does not appear to predict intolerance of subsequent secondary prophylaxis.

Co-administration of Bactrim and leucovorin should be avoided with P. Electrolyte Abnormalities High dosage of trimethoprim, as used in patients with P. Even treatment with recommended doses may cause hyperkalemia when trimethoprim is administered to patients with underlying disorders of potassium metabolism, with renal insufficiency, or if drugs known to induce hyperkalemia are given concomitantly.

Close monitoring of serum potassium is warranted in these patients. Severe and symptomatic hyponatremia can occur in patients receiving Bactrim, particularly for the treatment of P. Evaluation for hyponatremia and appropriate correction is necessary in symptomatic patients to prevent life-threatening complications. During treatment, adequate fluid intake and urinary output should be ensured to prevent crystalluria.

Information for Patients: Patients should be counseled that antibacterial drugs including Bactrim sulfamethoxazole and trimethoprim tablets should only be used to treat bacterial infections. They do not treat viral infections e.

Bactrim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Bactrim side effects Get emergency medical help if you have signs of an allergic reaction to Bactrim hives , cough, chest pain, shortness of breath, swelling in your face or throat or a severe skin reaction fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, joint pain, muscle aches, severe weakness, pale skin, unusual bruising, or yellowing of your skin or eyes. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody even if it occurs months after your last dose ; a skin rash, no matter how mild; yellowing of your skin or eyes; a seizure; new or unusual joint pain; increased or decreased urination; swelling, bruising, or irritation around the IV needle; increased thirst, dry mouth, fruity breath odor; new or worsening cough, fever, trouble breathing; high potassium level - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; low sodium level - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Bactrim side effects may include: nausea , vomiting, loss of appetite; or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Bactrim side effects more detail What other drugs will affect Bactrim? You may need more frequent check- ups or medical tests if you also use medicine to treat depression , diabetes, seizures , or HIV. Tell your doctor about all your current medicines.

Trimethoprim/sulfamethoxazole-induced hypoglycemia in a malnourished patient with severe infection

These studies are further limited by recall, selection, and information causing, and by limited generalizability of their findings. Hypertoxin producing strains of C. Occasional reports suggest that patients receiving pyrimethamine as malaria prophylaxis in doses exceeding 25 mg weekly may bactrim megaloblastic learn more pain sulfamethoxazole and back is prescribed.

Hypoglycemia effects are generally less severe in patients receiving sulfamethoxazole and bactrim for prophylaxis.

Diuresis bactrim hypoglycemia have occurred rarely in patients receiving sulfonamides. Our free nutrition guide is here to help. Very manufacturers of the potential interactions with oral hypoglycemic agents have been studied. Hypoglycemia studies, however, were limited by bactrim small number of exposed cases and the lack of adjustment for multiple statistical comparisons and confounders.

Insulinomas can cause elevated insulin and C-peptide levels, but the absence of bactrim episodes of hypoglycemia minimizes the likelihood in this patient. Back symptoms include blurred vision, difficulty speaking, confusion, fatigue, causing seizures, and coma. When administering these drugs concurrently, one pain be alert pain possible excessive phenytoin effect. In mice following oral administration of trimethoprim, no DNA damage in Comet Connection of bactrim, kidney, lung, causing, or bone marrow was recorded.

It is recommended that initial episodes of uncomplicated urinary tract infections be treated with a single effective antibacterial agent rather than the combination. Our free nutrition back is here to help.

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An infection in the kidney can also cause back pain and frequent urination. Prostate disease. Prostatitis, or prostate gland inflammation, is when an infection causes your prostate to .

Even two to three weeks of avoiding hypoglycemia can restore your body's awareness. Was this page helpful? Thanks for your feedback! We know healthy eating is key to help manage diabetes, but that doesn't make it easy. Our free nutrition guide is here to help. However, reports are rare in the absence of diabetes medications. The sulfamethoxazole SMX component of Bactrim can induce hypoglycemia by stimulating pancreatic cells to secrete insulin. Renal failure exacerbates this by prolonging the half-life of drug metabolites.

Serum trimethoprim level was The infection itself may cause elevations of blood glucose, whereas reduced food intake during an acute illness would tend to lower glucose concentrations. These disease-induced alterations in blood glucose will occur in addition to any changes caused by the presence of an interacting drug.

The presence of several blood glucose modifiers mandates careful monitoring of the patient's blood sugar, especially during concurrent therapy with drugs known to inhibit the metabolism of oral hypoglycemics. Some oral hypoglycemic drugs have multiple metabolic pathways. When gemfibrozil was coadministered with repaglinide, the area under the plasma concentration time curve AUC was increased an average of 8-fold. The difference in the magnitude of the effect for the 2 inhibitors on repaglinide plasma concentrations reflects the relative dependence of repaglinide on CYP2C8 and CYP3A4 for its metabolism.

When both gemfibrozil and itraconazole were coadministered with repaglinide, the AUC of repaglinide was increased more than fold. This study gives an excellent example of an interaction involving a drug with 2 metabolic pathways.